Three attackers wearing Afghan national security forces uniforms and armed with AK-47s and hand grenades, attacked. After shooting and killing a security guard at the hospital entrance, they entered the hospital and headed directly to the maternity ward, moving systematically from room to room. There were 28 women in the ward at the time. The attackers fired on patients and threw hand grenades. As a result of the attack, 24 people were killed, including 19 women and three children,35 and 23 more were injured, including 12 women, two children and one newborn. A female healthcare worker was amongst those killed in the attack.

On 15 June, the organization, Médecins Sans Frontiers (MSF), who operated the maternity ward, announced its decision to end activities and withdraw from Dasht-eBarchi hospital.